diff --git a/config.h.meson b/config.h.meson
index 948135f1c..f357085bc 100644
--- a/config.h.meson
+++ b/config.h.meson
@@ -428,11 +428,6 @@
    significant byte first (like Motorola and SPARC, unlike Intel). */
 #mesondefine WORDS_BIGENDIAN
 
-/* Enable large inode numbers on Mac OS X 10.5.  */
-#ifndef _DARWIN_USE_64_BIT_INODE
-# define _DARWIN_USE_64_BIT_INODE 1
-#endif
-
 /* Number of bits in a file offset, on hosts where this is settable. */
 #mesondefine _FILE_OFFSET_BITS